RESUMO
Background: Precious fruits like jambul are neglected and wasted while environmental pollutants like lead intake remain overlooked
Objective: The aim of this study was to investigate the effects of the Jambul pulp extract on lead detrimental effects in pseudostratified epithelium and the stereocilia of mice epididymis and vas deferens
Materials and Methods: Thirty young males mice [Mus musculus] were distributed randomly in 3 groups [n= 10] called control, Pb [Lead] and Pb-J [Lead-Jambul]. The Pb and Pb-J were provided 50ppm Pb in drinking water ad libitum for 15 days and Pb free water for the next 5 days. The Pb-J group received 0.2ml jambul pulp extract on 12 hourly bases. Control group was not given any treatment. Organs [epididymis and vas deference] were recovered on 21[st] days after euthanasia. The organs were finally processed for histological and micrometric studies
Results: Marked histologic and micrometric changes in both organs were noted in Pb group. These include significant [P
Conclusion: The results indicate that epididymis and vas deferens are highly sensitive to Pb exposure while Jambul pulp extract has shown rich mitigating potentials against such histopathologies